Adenosine Receptors and Wound Healing
نویسندگان
چکیده
منابع مشابه
Adenosine A2A receptors promote adenosine-stimulated wound healing in bronchial epithelial cells.
Adenosine produces a wide variety of physiological effects through the activation of specific adenosine receptors (A(1), A(2A), A(2B), A(3)). Adenosine, acting particularly at the A(2A) adenosine receptor (A(2A)AR), is a potent endogenous anti-inflammatory agent and sensor of inflammatory tissue damage. The complete healing of wounds is the final step in a highly regulated response to injury. R...
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The complete healing of wounds is the final step in a highly regulated response to injury. Although many of the molecular mediators and cellular events of healing are known, their manipulation for the enhancement and acceleration of wound closure has not proven practical as yet. We and others have established that adenosine is a potent regulator of the inflammatory response, which is a componen...
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www.PRSJournal.com 18S Wound healing is a multifaceted process governed by sequential yet overlapping phases, including hemostasis, inflammation, proliferation, and remodeling. This process is executed through communication between the various local skin compartments, supporting extracellular matrix, and systemic contributors. Under physiological conditions in a healthy individual, the process ...
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Oxygen is essential to several critical mechanisms in wound healing, including bacterial killing, angiogenesis, fibroplasia, and epithelialization. As a substrate, oxygen provides the respiratory burst necessary for white blood cells to kill engulfed bacteria, hastening resolution of inflammation so that a preliminary matrix can be formed for subsequent fibroplasia and epithelialization. Additi...
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ژورنال
عنوان ژورنال: The Scientific World JOURNAL
سال: 2004
ISSN: 1537-744X
DOI: 10.1100/tsw.2004.1